VQUIN
Preventing multi-drug resistant tuberculosis in a high prevalence setting: ‘Connecting the DOTS’ in Vietnam
STUDY SITES: Hanoi, Nam Dinh, Thanh Hoa, Khanh Hoa, Da Nang, Quang Nam, Ho Chi Minh City, Tien Giang, An Giang and Can Tho
TIMELINE: 2016 – 2020
PROJECT IMPLEMENTER: National Lung Hospital / National TB Program
FUNDED BY: National Health and Medical Research Council (NHMRC)
CORE STAKEHOLDERS: Provincial Lung Hospitals of 10 project provinces
PRINCIPAL INVESTIGATOR: Professor Greg Fox, The University of Sydney and the Woolcock Institute of Medical Research
VIETNAMESE PRINCIPAL INVESTIGATOR: Associate Professor Nguyen Viet Nhung, National Lung Hospital
PRIMARY OBJECTIVE: To test the effectiveness of levofloxacin given for 6 months, compared to placebo, in the prevention of active TB among household contacts of patients with MDR-TB who have latent tuberculosis infection.
This study was registered as a clinical trial under number: ACTRN12616000215426
Publications
Ototoxicity among multidrug-resistant tuberculosis patients: a systematic review and meta-analysis, The International Journal of Tuberculosis and Lung Disease